I am honored to have co-authored a chapter titled “Integration of patient-reported outcomes in industry-sponsored clinical trials” in the second edition of Oncology Clinical Trials.
In this study, our objective was to examine treatment patterns, possible statin intolerance, and incidence of cardiovascular events in patients with high cardiovascular risk - particularly ASCVD and type 2 diabetes.
In a follow-up of the Salford Lung Study (SLS) in COPD, RTI-HS researchers evaluated outcomes not traditionally examined in clinical trials and gained insight into patient experiences.
Parents of children diagnosed with a rare disease are faced with many difficult decisions. One that may be particularly challenging is whether they should enroll their child in an available clinical trial. We will be launching a project to develop a decision tool that elicits parents’ benefit-...
As a business unit of RTI International, RTI Health Solutions is proud to share that RTI has been named a "World's Most Ethical Company" for the second year in a row.
Good practices in health care research are continually evolving. Recently, there have been methodological advances in stated-preference methods.
Patients with highly active NMO had more than 10 times the number of hospitalizations during the study follow-up period, and their average length of stay was significantly longer than the matched control patients.
Stephanie Earnshaw, Senior Vice President of Health Economics for RTI Health Solutions (RTI-HS), is one of this year's Margaret Elliot Knox Excellence Award recipients for her outstanding contributions to RTI International.
Researchers collected and compared data of ventilated patients with and w/out ventilator-associated pneumonia (VAP) after heart surgery to determine the additional cost to treat patients who developed VAP.
How does the US compare against the rest of the world regarding GDP spending on health care?
A lot has happened in the ten years since the inception of ENCePP. Here’s what this European Medicines Agency supported network has achieved so far:
In the US, there are large disparities between racial and ethnic populations in HIV incidence, and levels of care. This research looks at how improving HIV care in all racial and ethnic groups would impact HIV incidence and measures of disparity.
Chronic migraines can be debilitating and may be associated with medication overuse, which makes it important that any treatment for the condition must be effective and well tolerated by patients. In Phase III clinical trials, onabotulinumtoxinA was shown to be safe for use as a preventative for...
Through presentation and hands-on exercises, participants will learn to design and build a budget impact model and interpret the results.
Carcinoid syndrome is caused by cancerous carcinoid tumors that secrete chemicals–including serotonin–into the bloodstream. These secretions can cause a variety of symptoms including frequent watery bowel movements (BMs). Telotristat ethyl, a serotonin inhibitor, was studied in the Phase III...
Angelman syndrome (AS) is a rare genetic disorder that causes a range of impairments. Affected individuals have severe to profound intellectual disabilities, seizures, behavioral issues, and challenges with communicating, walking, and sleeping.
New research also indicates that cost may override both factors for patients with most prevalent type of leukemia
Our goal for this study, was to demonstrate the advantages of using longitudinal data methods
Patients receiving chemotherapy frequently experience febrile neutropenia (FN), a dose-limiting toxicity that may disrupt planned chemotherapy administration (such as causing delays or dose reduction). This toxicity may necessitate hospitalization, which can be prolonged, costly, and may...
The UNC Gillings School of Global Public Health is doing something new. This fall for the first time, they are teaching a special topics course in pharmacovigilance as part of their pharmacoepidemiology curriculum.
Allen Mangel, MD, PhD, and Executive Vice President of RTI-HS, examines evidence that supports a different understanding of the behavior of the aorta during the cardiac cycle. Article published in J of Cardio Pharma.
Patient preference has the potential to inform a host of issues from initial device or drug development to post-marketing surveillance. While patient preference studies in health care research are becoming common, their use in regulatory decision making is relatively new.
Several members of the RTI-HS team recently attended the National Institute for Health and Care Excellence (NICE) 2017 conference in Liverpool, UK—a valuable way for our team to stay abreast of updates and ensure we have the appropriate understanding to guide our clients through the ever-...
The risks associated with respiratory syncytial virus (RSV) in newborns are generally well known. Parents of infants – particularly babies who were born prematurely – are routinely educated on precautions to protect their newborns against exposure, and pediatricians are vigilant about...
Recent law updates medical device regulation in the US. In the EU - greater transparency in post-market follow-up.