The PSA test is used to screen men for prostate cancer, however there is controversy around its poor sensitivity and specificity. It can lead to unnecessary biopsies and the overtreatment of low-grade cancers.
Communication of Pre-approval Information by Drug and Device Manufacturers to Payers in the US
It’s no longer business as usual. We are entering a new era of capturing patients’ voice in cancer drug development. It is critical to remain abreast of trends in the regulatory environment. Ari Gnanasakthy shares takeaways from FDA/ASCO workshop.
This new book serves as an essential reference for pharmacovigilance scientists and pharmacoepidemiologists searching for the appropriate study design to answer safety research questions in studies required by regulators. Two RTI Health Solutions (RTI-HS) researchers are contributors.
Biopharmaceutical Innovation Has Significant Impact, According to Physicians Surveyed. A recent survey of U.S. physicians provides insight on their perceptions regarding the impact of medical innovation on outcome
Soft tissue sarcoma (STS) is a rare group of malignant tumors comprising more than 50 histologic subtypes that are derived from connective tissues and other cells of mesenchymal origin. They account for approximately 1% of all incident malignancies.
Understanding What Matters Most to Alzheimer's patients and their caregivers to help inform the drug development process.
The Alzheimer’s Disease Patient and Caregiver Engagement (AD PACE) initiative is a first-of-its-kind collaboration among pharmaceutical companies, advocacy...
Research team members each have their own areas of expertise, which may not include experience with raw data. They all need tools they can understand to help them assess the data.
A small subgroup who have been on HIV treatment a long time have developed resistance to most currently available treatments
Guidelines for economic systematic reviews are sparse, and those available mainly focus on economic evaluations or health state utility values.
Most patients reported that the benefits of their therapy met or exceeded their expectations
Relationship Between Compliance & Blindness Prevention in Diabetic Retinopathy Screening
CDFs and PDFs: Comparing Visual Methods Supporting Responder Thresholds in Clinical Trials
Research: Programmed Cell Death LIGAND-1 Testing Among Patients with Metastatic Non-Small Cell Lung Cancer
Research: Prescription Opioid Use Among Children and Adolescents with Asthma
Should affordability of new drug and medical technology be managed within current budgets, should we raise premiums or taxes, or should payors rely on price negotiations?
I am honored to have co-authored a chapter titled “Integration of patient-reported outcomes in industry-sponsored clinical trials” in the second edition of Oncology Clinical Trials.
In this study, our objective was to examine treatment patterns, possible statin intolerance, and incidence of cardiovascular events in patients with high cardiovascular risk - particularly ASCVD and type 2 diabetes.
In a follow-up of the Salford Lung Study (SLS) in COPD, RTI-HS researchers evaluated outcomes not traditionally examined in clinical trials and gained insight into patient experiences.
Parents of children diagnosed with a rare disease are faced with many difficult decisions. One that may be particularly challenging is whether they should enroll their child in an available clinical trial. We will be launching a project to develop a decision tool that elicits parents’ benefit-...
As a business unit of RTI International, RTI Health Solutions is proud to share that RTI has been named a "World's Most Ethical Company" for the second year in a row.
Good practices in health care research are continually evolving. Recently, there have been methodological advances in stated-preference methods.
Patients with highly active NMO had more than 10 times the number of hospitalizations during the study follow-up period, and their average length of stay was significantly longer than the matched control patients.
Stephanie Earnshaw, Senior Vice President of Health Economics for RTI Health Solutions (RTI-HS), is one of this year's Margaret Elliot Knox Excellence Award recipients for her outstanding contributions to RTI International.