Barnett C, Denton BT, Montie JE. Developing optimal biomarker-based prostate cancer screening policies. Presented at the 2015 INFORMS Annual Meeting; November 2, 2015. Philadelphia, PA.


Recent advances in the development of new biomarker tests, which physicians use for the early detection of cancer, have the potential to improve patient survival by catching cancer at an early stage. We describe a partially observable Markov decision process (POMDP) to compute near optimal prostate cancer screening strategies. We present results based on Monte Carlo simulation to compare the policies developed using our approximated POMDP methods with those recommended in the medical literature.

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