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… Psychometric Evaluation Our psychometricians have extensive experience … Our psychometric services include: Psychometric analyses using both classical and modern psychometric methods, … Theory Psychometric evaluations based on clinical trial or observational study data Cross-sectional and longitudinal …
… Conducting feasibility assessments for studies using databases and/or primary data collection Developing … consulting support for specific projects or can set up long-term arrangements that allow access to specific experts on an …
… Observational Studies Analyzing real-world, observational … are knowledgeable in the unique designs and statistical techniques necessary to analyze studies using these types of data sources. Our researchers have the …
… Assess Long-Term Treatment Effects with Pooled Database Analysis Share … this treatment with standard of care over a longer period using existing clinical research data. The developer had data … phase 3 studies, treatment extension studies, and observational studies. While the individual studies had …
… Surveys and Observational Studies Beyond the evidence standards set by … clinical trials, well-designed and implemented surveys and observational studies can help you, your patients, … and retention Statistical analysis plans Reports and publications Data Collection and Management Depending upon …
… Pooled Data Analysis of Long-Term Treatment Effect OPPORTUNITY Our client had a treatment … rate of decline in kidney function over a longer period, using existing clinical trial data. THE CHALLENGE Our client …
… for estimating the product's safety and/or effectiveness using real-world data (RWD). This most often involves causal … target trial has been specified, we attempt to emulate it using RWD. Such emulation may be methodologically simple, or … external researchers to apply the target trial framework using diverse types of real-world data. See examples of …
… We conduct literature reviews and meta-analyses using the most rigorous methodologies, so you get reliable … HTA submissions . We are trained in state-of-the art techniques to design and perform meta-analyses using a … responses including a mixture of binomial and ordinal data Survival outcomes Poisson outcomes including epidemiological …
… Integrated Real-World Clinical and Economic Evaluation of Treatment Alternatives OPPORTUNITY … to leverage real-world effectiveness data to compare the long-term clinical and economic value of various DMTs for MS. … in comparison with a common reference group to facilitate extrapolation scenarios in the cost-effectiveness model. We …
… efficacy. Other challenges included understanding long-term treatment efficacy, identifying appropriate treatment stopping rules, finding publications reporting stratified cost and utility estimates, …